Vanderbilt University
Congratulations Julius on being named Outstanding Senior Organic Chemistry Student by the ACS & VU's Outstanding Chemistry Researcher!
Congrats to Paige Thorpe and all of our collaborators on the occasion of our interdisciplinary work recognized as the Top Original Research Paper of 2023!
Welcome Chloe Vernon, Cody Funk, Destiny Harrison, & Yi-Ching Lin, our new G1's!
Congratulations to Dan Sprague (Ph.D. 2016) who landed a position at the Medical University of South Carolina in Charleston as an Assistant Professor of Biochemistry and Molecular Biology.
Congrats to the group on their top 10% designation in the Merck Synthesis Challenge!
Look for Team Catalysis' latest in the J. Am. Chem. Soc. 2024, 146, 1269
Our pharmacokinetic (PK) study of ent-B1 in vivo published in the J. Pharm. Exptl. Ther. 2023, 385, 205
Congratulations Julius on being named Outstanding Senior Organic Chemistry Student by the ACS & VU's Outstanding Chemistry Researcher! Congrats to Paige Thorpe and all of our collaborators on the occasion of our interdisciplinary work recognized as the Top Original Research Paper of 2023! Welcome Chloe Vernon, Cody Funk, Destiny Harrison, & Yi-Ching Lin, our new G1's! Congratulations to Dan Sprague (Ph.D. 2016) who landed a position at the Medical University of South Carolina in Charleston as an Assistant Professor of Biochemistry and Molecular Biology. Congrats to the group on their top 10% designation in the Merck Synthesis Challenge! Look for Team Catalysis' latest in the J. Am. Chem. Soc. 2024, 146, 1269 Our pharmacokinetic (PK) study of ent-B1 in vivo published in the J. Pharm. Exptl. Ther. 2023, 385, 205
Since 1999, we have been uncovering new modes of reactivity and applying these discoveries in chemistry to the development of fundamentally new concepts in enantioselective catalysis and basic reaction development. Complex natural product total synthesis is the beginning and end of the project development cycle, and we have more recently succeeded in applying our discoveries to the de novo synthesis of therapeutics. These pages summarize some accomplishments across the areas of target synthesis, therapeutic development, and enantioselective catalysis. With several colleagues in biochemistry, cancer biology, and drug development, we collaboratively advance the discipline of chemical biology to leverage the power of chemical synthesis, thereby clarifying our basic understanding of the pathology and treatment of disease.