Vanderbilt University
Two pubs landed in Summer 2024 that describe how Paige led a collaboration to identify backbone-modified analogs of ent-verticilide to study their cell permeability (Chem Sci) and antiarrhythmic activity (J Med Chem) - check them out!
Congratulations Julius on being named Outstanding Senior Organic Chemistry Student by the ACS & VU's Outstanding Chemistry Researcher!
Congratulations to Dan Sprague (Ph.D. 2016) who landed a position at the Medical University of South Carolina in Charleston as an Assistant Professor of Biochemistry and Molecular Biology.
Congrats to the group on their top 10% designation in the Merck Synthesis Challenge!
Look for Team Catalysis' latest in the J. Am. Chem. Soc. 2024, 146, 1269
Two pubs landed in Summer 2024 that describe how Paige led a collaboration to identify backbone-modified analogs of ent-verticilide to study their cell permeability (Chem Sci) and antiarrhythmic activity (J Med Chem) - check them out! Congratulations Julius on being named Outstanding Senior Organic Chemistry Student by the ACS & VU's Outstanding Chemistry Researcher! Congratulations to Dan Sprague (Ph.D. 2016) who landed a position at the Medical University of South Carolina in Charleston as an Assistant Professor of Biochemistry and Molecular Biology. Congrats to the group on their top 10% designation in the Merck Synthesis Challenge! Look for Team Catalysis' latest in the J. Am. Chem. Soc. 2024, 146, 1269
Since 1999, we have been uncovering new modes of reactivity and applying these discoveries in chemistry to the development of fundamentally new concepts in enantioselective catalysis and basic reaction development. Complex natural product total synthesis is the beginning and end of the project development cycle, and we have more recently succeeded in applying our discoveries to the de novo synthesis of therapeutics. These pages summarize some accomplishments across the areas of target synthesis, therapeutic development, and enantioselective catalysis. With several colleagues in biochemistry, cancer biology, and drug development, we collaboratively advance the discipline of chemical biology to leverage the power of chemical synthesis, thereby clarifying our basic understanding of the pathology and treatment of disease.